Due to the risk for serious and potentially permanent side effects associated with fluoroquinolone antibiotics, moxifloxacin should only be used in cases where alternative treatment options cannot be used. Dailymed vigamox moxifloxacin hydrochloride solution. Avelox iv 250 ml flexibag containing 400 mg moxifloxacin hydrochloride in. Vigamox moxifloxacin hydrochloride ophthalmic solution. Moxifloxacin hydrochloride cas 186826868 scbt santa. View all certificates of suitability cepcos of moxifloxacin hydrochloride api filed with the edqm on. Moxifloxacin is a 8methoxy quinolone and differs from other quinolones. Remove contact lenses, if present and if it is easy to do.
Application moxifloxacin hydrochloride has been used to study its antibacterial action against bacteria that have grown to high density. Aug 01, 2019 moxifloxacin tablets usp are available as filmcoated tablets containing moxifloxacin hydrochloride equivalent to 400 mg moxifloxacin. Material safety data sheet of moxifloxacin contains identification of substance and details of the supplier of the safety data sheet. Twentyfive patients from the moxifloxacin hydrochloride clinical datapool 7284 patients had an episode of atrial fibrillation. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle.
Moxifloxacin hydrochloride is an antibiotic prescription medicine approved by the u. Moxifloxacin hydrochloride definition of moxifloxacin. Sigmaaldrich offers a number of moxifloxacin hydrochloride products. The model drug moxifloxacin hydrochloride was loaded into hydrogels films and drug release was studied at ph 7. Find patient medical information for moxifloxacin oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. New zealand data sheet avelox moxifloxacin 1 product name avelox 400 mg moxifloxacin film coated tablet avelox 400 mg moxifloxacin solution for infusion 2 qualitative and quantitative composition each tablet contains 436.
Moxifloxacin hydrochloride is the hydrochloride salt preparation of moxifloxacin, an 8methoxyfluoroquinone compound with broadspectrum bactericidal activity against grampositive and gramnegative strains. Moxifloxacin, a fluoroquinolone, is available as the. Moxeza is a sterile solution for topical ophthalmic use. Moxifloxacin hydrochloride uses, side effects aidsinfo. Moxifloxacin hydrochloride cas 186826868 msds guidechem. Nda 21598 page 3 vigamox moxifloxacin hydrochloride ophthalmic solution 0. When an infection occurs within the body, bacteria multiply quickly and release chemicals that build up and lead to illness and, in severe cases, death. Avelox tablets are available as filmcoated tablets containing moxifloxacin hydrochloride equivalent to 400 mg moxifloxacin.
In case of skin contact wash off with soap and plenty of water. Moxifloxacin was subsequently ten years later approved by the fda for use in the united states in 1999. Moxifloxacin hydrochloride is an 8methoxy fluoroquinolone antiinfective, with a diazabicyclononyl ring at the c7 position. Serious adverse reactions fluoroquinolones, including moxifloxacin, have been associated with disabling and potentially irreversible serious adverse reactions e. At least four additional united states patents have been filed regarding moxifloxacin hydrochloride since the 1989 united states application, as well as patents outside of the usa. Moxifloxacin tablets fda prescribing information, side. Moxifloxacin is a fluoroquinolone antibiotic with antibacterial activity. Moxifloxacin was not mutagenic in four bacterial strains used in the. In case of eye contact flush eyes with water as a precaution.
Product name moxifloxacin hydrochloride sigmaaldrich. Wash eyes with plenty of clean and cool water for at least 10 minutes while pulling eyelids up, and seek medical assistance. The inactive ingredients are microcrystalline cellulose, mannitol, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide and polyethylene glycol. Moxifloxacin hydrochloride oral tablet 400mg drug medication. Moxifloxacin hydrochloride monograph for professionals. Moxifloxacin hydrochloride sc205758 hazard alert code key. Jul 17, 2019 moxifloxacin hydrochloride tablets are indicated in adult patients for the treatment of acute bacterial exacerbation of chronic bronchitis abecb caused by susceptible isolates of streptococcus pneumoniae, haemophilus influenzae, haemophilus parainfluenzae, klebsiella pneumoniae, methicillinsusceptible staphylococcus aureus, or moraxella. Moxifloxacin binds to and inhibits the bacterial enzymes dna gyrase topoisomerase ii and topoisomerase iv, resulting in inhibition of dna replication and repair and cell death in sensitive bacterial species. Vigamox moxifloxacin hydrochloride ophthalmic solution 0. The harmonized system hs code provided on this webpage are for information purposes only and are subject to change without notice.
Moxifloxacin is a fourthgeneration synthetic fluoroquinolone antibacterial. Moxifloxacin hydrochloride investigated as a drug and mutagen. New zealand data sheet avelox moxifloxacin 1 product name. Capitals indicate lifethreatening, underlines indicate most frequent. Material may be irritating to the mucous membranes and upper respiratory tract. Inquire about dmf, cgmp, price, availability, samples, sourcing, purity and more. Sds of moxifloxacin hydrochloride, safety data sheets, cas. Review of moxifloxacin hydrochloride ophthalmic solution in. Material safety data sheet of moxifloxacin abmole bioscience. All of the genetic material that drives the bacteria to. Aidsinfo provides the following drug label solely as an example of the labels available for moxifloxacin hydrochloride. It is an 8methoxy fluoroquinolone antiinfective for topical ophthalmic use.
The inactive ingredients are microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, polyethylene glycol and ferric oxide. Search results for moxifloxacin hydrochloride at sigmaaldrich. The company added that its moxifloxacin hydrochloride tablets, 400 mg is the therapeutic equivalent generic version of avelox moxifloxacin hcl tablets 400 mg. See actual entry in rtecs for complete information. Only select registry of toxic effects of chemical substances rtecs data is presented here. Moxifloxacin hydrochloride vetranal, analytical standard. Quinolones are antibiotics that treat a variety of bacterial infections. This compound is currently being examined as a conjunctive therapy with anticancer agents against several forms of cancer due to its topoisomerase ii inhibition. Product details for 85126157 moxifloxacin hydrochloride 186826868 moxifloxacin hydrochloride catalog molekula group. Injection solution several fdaapproved drug labels may be available for moxifloxacin hydrochloride. Safety data sheet 109200 moxifloxacin hydrochloride. Mar 18, 2019 moxeza moxifloxacin hydrochloride ophthalmic solution. The prepared hydrogel films were evaluated for the carboxyl content and swelling ratio. The hemolysis assay was used to study the biocompatibility of hydrogel films.
Food and drug administration fda for the treatment of certain bacterial infections, such as acute worsening of chronic bronchitis, acute sinus infections, communityacquired pneumonia, plague, and skin and abdominal infections. The model drug moxifloxacin hydrochloride was loaded into hydrogels films and drug release was studied at ph. Moxifloxacin hydrochloride oral tablet 400mg drug medication dosage information. Moxifloxacin hydrochloride revision date 23jan2018 precautionary statements prevention wash face, hands and any exposed skin thoroughly after handling do not eat, drink or smoke when using this product wear eyeface protection eyes if in eyes. Moxifloxacin, hydrochloride monohydrate cas 192927632. Moxifloxacin hydrochloride fda label injection solution. The model drug moxifloxacin hydrochloride was loaded. Moxifloxacin hydrochloride is a synthetic broad spectrum antibacterial. In 4 of these patients the relationship between the event and moxifloxacin hydrochloride therapy was assessed as possible, though in each case it could also be explained by preexisting cardiac disease.1184 28 1201 342 160 1150 866 200 203 211 972 559 1400 1247 252 1388 1474 167 56 1478 220 96 275 683 526 508 798 1104 1393 196 27